Only you can judge the seriousness of this -- but if it's interfering with your daughter's schoolwork and upsetting her in more than a passing way, then it would be entirely appropriate to share your concern with her teacher.
Bullying isn't acceptable today, and even if their taunts don't go that far, those who are involved need to learn to be more considerate of others. If they don't learn this, they'll go through life with a critical and arrogant attitude -- and no one really wants someone like that for a friend. The Bible commands us "to slander no one, to be peaceable and considerate, and to show true humility toward all men" (Titus 3:2).
Help your daughter not take what these classmates are saying too seriously. At her age, young people want to be accepted by others; no teenager likes to be rejected. This makes situations like this doubly hard for them. Let her know you love her just as she is, and help her realize she has unique gifts and abilities that others don't have.
Most of all, encourage her to begin seeing herself the way God sees her. God loves her; He loves her so much that He sent His Son into the world to give His life for her. Encourage her to give her life to Christ, and then to thank God that she is now His child. Her life will never be the same once she sees herself from God's point of view.